منابع مشابه
The miR-200 family in ovarian cancer
Ovarian cancer (OC) is the most lethal gynecological malignancy. Its insidious nature, manifesting with little to no symptoms until the disease progresses to metastasis, along with a wide diversity of histological subtypes and corresponding clinical behavior, poses significant therapeutic challenges. The genetic profiling of this aggressive tumor and its subtypes has led to the identification o...
متن کاملBioinformatics Study of the miR-200 Family and the Target Genes in Prostate Cancer
Introduction: Considering the limitations of the common diagnostic test for prostate cancer prostate cancer, the introduction of higher-specific biomarkers for a more accurate and timely diagnosis of prostate cancer is desired. In this study, we aimed to investigate the miR-200 family (miR-200a, miR-200b, miR-200c, miR-141, and miR-429) and their target genes using bioinformatics prediction too...
متن کاملBioinformatics Study of the miR-200 Family and the Target Genes in Prostate Cancer
Introduction: Considering the limitations of the common diagnostic test for prostate cancer prostate cancer, the introduction of higher-specific biomarkers for a more accurate and timely diagnosis of prostate cancer is desired. In this study, we aimed to investigate the miR-200 family (miR-200a, miR-200b, miR-200c, miR-141, and miR-429) and their target genes using bioinformatics prediction too...
متن کاملmiR-200 family promotes podocyte differentiation through repression of RSAD2
Mature podocytes are highly differentiated cells with several characteristic phenotypic features that are involved in the glomerular filtration function. During kidney development, a series of changes of the morphological characteristics and cellular functions may happen in podocytes. The miR-200 family functions in various biological and pathological processes. But the underlying molecular mec...
متن کاملThe miR-200 Family: Versatile Players in Epithelial Ovarian Cancer
The role of microRNAs (miRNAs or miRs) in the pathology of epithelial ovarian cancer (EOC) has been extensively studied. Many miRNAs differentially expressed in EOC as compared to normal controls have been identified, prompting further inquiry into their role in the disease. miRNAs belonging to the miR-200 family have repeatedly surfaced over multiple profiling studies. In this review, we attem...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2011
ISSN: 2219-2859
DOI: 10.11569/wcjd.v19.i29.3053